Johnny Depp left his imprint on Hollywood Boulevard over the weekend -- hitting the ground HARD after leaving a late night grub session Saturday night.
Depp seemed a little woozy as he left a fancy gastropub called 25 Degrees ... and while his friend tried to escort the actor to a waiting SUV, they both crashed hard to the pavement.
Johnny got up ... and eventually made it to the car, where he flashed some kind of random salute to the paps ... apparently meaning he was okay.